MD, Paediatrician and PhD in Virology, she heads the Viral Evolution and Transmission Unit, at the San Raffaele Scientific Institute. She was Science Director of the Global HIV Vaccine Enterprise, in New York, and Director of the Division of B cell and mucosal immunity of the Vaccine Research Institute, in Paris.
Since 1994 she works as a scientist and her laboratory is interested on the virologic and immunologic mechanisms of mother-to-child transmission of HIV and paediatric and adult infections to identify molecular signatures relevant for prevention of infection and containment of disease. She coordinated and still coordinates HIV vaccine projects and humoral immunity platforms of international consortia, which are aimed at developing new immunogens to induce broadly neutralizing antibodies. She has served on numerous international scientific and working committees. She enjoyed supervising and working with graduate students and PhD students, and acted as opponent or examiner for Ph.D. thesis defenses worldwide.